Each formulation developed at InhaTarget Therapeutics shows specific aerodynamic properties maximizing the deposited dose in the lungs, for an optimized efficacy and posology of the drug.
Many molecules present systemic dose limiting toxicities requiring to spread their intake and hence impacting their efficiency on targeted organs. A local delivery, through the pulmonary route for lung diseases is an excellent solution to overcome the systemic limitations and bring a real added value in terms of drug efficiency (higher doses reaching the target organ, higher frequency of treatment,…)
While the molecules currently available as standard of care present a certain efficacy, innovative formulations, build around.(i) their physical and chemical properties and.(ii) their intended mechanism of action, enable to enhance their therapeutic outcome or to improve their safety profile.
All development preformed at InhaTarget therapeutics are driven by an optimal leverage of the immunogenic properties of our compounds. The inhalation route, combined with a specific formulation strategy allows to unleash the immune properties from existing molecules in the lungs.
Every molecule and indication requires a tailored formulation strategy and the selection of the appropriate inhalation method and device. InhaTarget Therapeutics experts focus on developing the optimized formulations, adapted to the most appropriate inhalation method for the intended use, to improve the properties and mechanism of action of existing molecules.
Patients’ well-being is always at the center of any product development initiatives at Inhatarget Therapeutics. The inhalation route and the developed drug delivery systems provide a real opportunity to bring a novel treatment modality (with an optimized benefit/risk ratio) to patients while preserving their daily comfort (non-invasive administrations, less systemic toxic effects, autonomy of treatment, home treatment).
Our inhalation expertise is driven by two objectives: improve the therapeutic outcome of effective molecule by changing their modality (route of administration, exposure, frequency, immunogenic properties) and improve the quality of life of severely diseased patients (administration at home, user-friendly and non-invasive treatment, …).
A dry powder formulation platform based on particle engineering technologies, at the origin of the chemo-DPI products.
A nanomedicine-based drug delivery technology enabling the optimal administration of immunotherapy to the lungs.